Blar i forfatter "Djordjilovic, Vera"

Viser treff 1-2 av 2

    • Global test for high-dimensional mediation: Testing groups of potential mediators 

      Djordjilovic, Vera; Page, Christian Magnus; Gran, Jon Michael; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Veierød, Marit Bragelien; Thoresen, Magne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-09)
      We address the problem of testing whether a possibly high‐dimensional vector may act as a mediator between some exposure variable and the outcome of interest. We propose a global test for mediation, which combines a global test with the intersection‐union principle. We discuss theoretical properties of our approach and conduct simulation studies that demonstrate that it performs equally well or ...

    • Lifetime ultraviolet radiation exposure and DNA methylation in blood leukocytes: The Norwegian Women and Cancer Study 

      Page, Christian; Djordjilovic, Vera; Nøst, Therese Haugdahl; Ghiasvand, Reza; Sandanger, Torkjel M; Frigessi Di Rattalma, Arnoldo; Thoresen, Magne; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel, 2020-03-11)
      Ultraviolet radiation (UVR) exposure is a leading cause of skin cancers and an ubiquitous environmental exposure. However, the molecular mechanisms relating UVR exposure to melanoma is not fully understood. We aimed to investigate if lifetime UVR exposure could be robustly associated to DNA methylation (DNAm). We assessed DNAm in whole blood in three data sets (n = 183, 191, and 125) from the Norwegian ...